Our dedicated PhD Program in Cancer Biology is one of the most established in the country and is supported by an NCI training grant in addition to valuable support from foundations and private donors allowing us to continue torecruit and train the next generation of expert cancer biologists.
We provide doctoral students with the most up-to-date knowledge and research training with the goal of preparing them for leadership and research careers in academia, industry, clinical research, science journalism, advocacy and policy, and other relevant areas of the biomedical workforce.
With 61 faculty members from across the Biological Sciences Division with diverse interests in all of these research areas, students have a broad choice of research concentrations to select from for their thesis research project. Our program has enabled many of our trainees to publish their work in outstanding journals and go on to run their own research labs.
Preparing students to conduct research : Our core curriculum focuses on multiple aspects of cancer biology, including:. Biochemist Donald F. The finding led to the synthetic production of human insulin, markedly improving therapy for diabetes sufferers, and laid the groundwork for improved understanding of how other proteins in the body are made.
In a series of investigations starting inRobert R. Bensley demonstrated that the islets of Langerhans were specialized elements of the pancreas. He developed staining methods that distinguished between alpha cells and the beta cells that produce insulin. Bensley's work was fundamental to the discovery of insulin. He later developed techniques to disassemble cells and isolate cellular components by spinning them in a centrifuge, a technique he used in to isolate mitochondria.
She later was a key player in the development of the first precisely targeted anti-cancer drug. Building on the work of cancer researcher Charles B. Huggins, Elwood Jensen and fellow medical researcher Eugene Desombre identified the precise mechanism through which hormones drive cancer—by binding to a receptor protein in cells.
The finding opened a new therapeutic front in breast cancer, leading to targeted treatments credited with saving many lives each year. Inmedical researcher Leon O. He discovered he could save a mouse whose bone marrow and spleen had been destroyed by transplanting donated spleen tissue into the mouse.
The procedure now helps thousands of patients with cancer and other diseases each year. Skip to main content. At the University of Chicago I found a welcoming community of students and faculty that can help me excel in my professional career as a scientist.
When applying to programs I focused on finding a place with great research opportunities that would also provide me with tools to succeed as a young scientist, and I found it here at UChicago. Explore our programs. Cancer Biology.
Preparing students to conduct research : Our core curriculum focuses on multiple aspects of cancer biology, including: molecular mechanisms of cancer tumor progression and metastasis autophagy and tumor metabolism cancer genomics computational approaches and big data analysis mechanisms of drug resistance tumor heterogeneity translational research approaches.
Faculty in Cancer Biology. Program Website. Related Programs.About Ph. My Moffitt. Life in Tamp Bay. The Cancer Biology PhD Program offers four distinct but closely integrated majors designed to prepare young scientists to meet the future challenges of cancer research.
Visit us at moffitt. Each major in the Program utilizes an integrated curriculum that provides specialize training in the area of focus plus broader training across the cancer research spectrum encompassing immunology, immunotherapy, cancer genetics, cell and molecular biology, signal transduction, drug discovery, chemical biology, mathematical modeling, functional genomics, proteomics, bioinformatics, chemistry, and translational cancer therapies.
Cancer Biology Major moffitt.
Applications received after December 1st may not be considered for funding so please apply early! The Research Accomplishment Award, which is presented to a student who has displayed exceptional research productivity during the year, was awarded to Shonagh Russell. She has an outstanding publication record, including two first author papers, Scientific Reports and Life at the Edge, that clinched the award! Well done, Shonagh! Alycia Gardner right and her mentor, Dr. This award is voted on by CBSO members and recognizes a student who has significantly contributed to the advancement of the Cancer Biology Student Organization.
Thank you to all the students who helped make the evening a success! Program Spotlight Archive Graduates. Nick Gimbronementored by Dr. Doug Cress successfully defended and graduated in Rebecca Hesterbergmentored by Dr.
PK Burnette successfully defended and graduated in Kamira Maharajmentored by Dr. Javier Pinilla Ibarz successfully defended and graduated in Eduardo Sotomayer and Dr. Lou-Ella Alexandermentored by Dr. Kenneth Wright successfully defended and graduated in Program Directors: Dr. Cancer biology is an academic discipline with a tangible end point: improving the prevention, diagnosis and treatment of human cancers.
The Program in Cancer Biology provides students interested in pursuing a career in cancer biology with rigorous training in biochemistry, genetics, molecular and cell biology, as well as an understanding of the clinical aspects of cancer.
The program is based in the Department of Cancer Biology, but it also includes faculty from most basic science departments and several clinical departments.
The strength and diversity of the faculty enable students to explore different approaches to the study of cancer in their laboratory rotations and to develop inter-departmental and interdisciplinary collaborations during their thesis research. This program is also an integral component of the Cancer Center of Excellence and it affords students the opportunity to participate in disease-based programs of the Cancer Center that are designed to translate achievements from the basic sciences to the clinical management of human cancers.
In addition to the required core curriculum, students will take three specific courses: Histology and Tumor Pathology, Cancer Medicine and Therapeutics, and Cancer Biology. Requirements for Specialization In addition to the required core curriculum, students will take three specific courses: Histology and Tumor Pathology, Cancer Medicine and Therapeutics, and Cancer Biology.Given the unique environment of the Texas Medical Center, the philosophy of the Cancer Biology Program is to supplement traditional graduate school training with both depth and breadth of knowledge in cancer biology.
Students will follow the standard format of choosing a single mentor who will guide an independent research project.
Division of Cancer Biology
However, our students frequently use the resources and expertise of several laboratories in different departments during the development of their cancer-related dissertation projects. This training provides a rich experience that increases the expertise and competitiveness of our graduates.
Currently, we have about 70 students and faculty affiliated with the program. Our students have been among the most outstanding and productive of the GSBS. They also have been the recipients of many GSBS awards, as well as nationally competitive awards and fellowships. Like the faculty, the students bring wide-ranging perspectives and goals to their research.
The program excels in accommodating these interests while fostering interactions among all of our students. The program faculty are eager to train motivated students, and will gladly provide additional information with respect to their research programs and training opportunities in their laboratories. This is an exciting new era in cancer research. A systematic training in cancer biology should allow our students to meet the challenge of Making Cancer History.
Hite Fellowship Rosalie B. Heath, Jr. John J.
Stancel, Ph. Arlinghaus, Ph. John Hancock, PhD Dr. Fellowship in Biomedical Sciences R. Butcher Student Achievement Scholarship. Clin Cancer Res. Epub Aug 3. PMID: Epub Feb Clin Nucl Med. Cell Rep. Epub Jan Skip to content. Cancer is a devastating disease. The American Cancer Society estimates that inalmost 1. Clearly we need to learn more about its causes, treatment, and prevention. The Doctoral Program in Cancer Biology at the University of Michigan is an interdisciplinary program whose goal is to train the next generation of cancer researchers.
We achieve this goal by providing students with the knowledge and critical thinking skills that will allow them to tackle the most pressing problems associated with this disease. Drawing on the talents of faculty mentors who are leading experts in the field, together with the substantial resources of the University and its NCI-designated Rogel Cancer Center, students pursue dissertation projects at the cutting edge of cancer biology. A pril Solon Ohi Lab. Mengrou Shan Lyssiotis Lab.
Thank you to all of you who participated in these competitions and congratulations to the recipients!Cancer Metabolism: From molecules to medicine
News January 15, Timothy Graubert Lunch With Trainees. November 6, Sheila Stewart Lunch With Trainees. September 13, You will train with faculty members who have a prestigious record of achievement in advancing understanding of gene regulation, hormone action and cell signaling, genomics, proteomics, metabolomics, cancer-related immune therapies and reproductive medicine.
We have incorporated the best elements of traditional graduate programs — academic rigor and stellar faculty — with flexibility that supports intensive academic training in small group formats while providing you the freedom and support necessary to design an individualized curriculum. Our program will give you the background and expertise needed to succeed in your scientific and professional career.
Whatever your vision for your career entails, we will provide the training, resources and support to help you realize your ambition. A fusion gene is a new gene made by joining parts of two different genes. It had been thought that fusion genes precede fusion RNA, but some have raised doubts that this is always the case. Until this study, researchers had yet to come forward showing that this proposed RNA-mediate gene rearrangements also happen in mammalian cells.
Although chemotherapy can fight back cancer, it also has been associated with increased risk of leukemia years after the treatment.
What leads to that association is not clear, but a recent report has provided some answers. The answers involve a gene called PPM1Dwhose function in blood production was unknown. The implications of these findings can affect the choice of chemotherapies.
Baylor M. Baylor researchers discovered a new major class of cancer-promoting genes by showing that many normal proteins made by our cells can act like carcinogens, damaged DNA and causing mutations. Former graduate student and current postdoctoral associate at Baylor, Dr.
Jun Xia was one of the two co-first authors on this study. Cells have in place a number of mechanisms to protect the integrity of the genome, including processes that repair mistakes that may occur during DNA replication.
The enzyme Dna2 participates in DNA repair, but little is known about the consequences of its absence on chromosome instability. In this project, Baylor researchers worked with yeast and discovered a mutant that shows frequent insertions of DNA fragments in DNA breaks.
This mutant lacks Dna2. They focused on finding ways to disrupt the effects of a class of protein called Ras, powerful drivers of a wide range of cancers. The Warburg effect has been a mystery for quite some time. Why would cancer cells, which need large amounts of energy to sustain their growth, prefer to use a pathway that produces less ATP than another available pathway?
What would be the advantage for cancer cells to use the Warburg pathway? This study sheds new light on this mystery. Historically, cancer patients have been classified according to the organs where primary tumors present at diagnosis, and clinical trials commonly test drugs that are designed to target cancers in a specific organ as well.
For breast cancer, carrying protein CD44s, instead of CD44v, has a survival advantage. Researchers have now discovered a mechanism by which cells can regulate switching between the two proteins, opening options for the development of novel therapeutic strategies to control cancer growth in the future. Scientists have been looking for receptors — molecules on cancer cells — that promote the growth of cancers.
But the receptors driving some cancer types like triple negative breast cancer TNBC have remained elusive to scientists, until now.
In order to earn this grant, our program successfully demonstrated that we provide high-quality research training, mentored research experiences, and additional training opportunities that equip trainees with the technical e.
Baylor College of Medicine is a health sciences university that creates knowledge and applies science and discoveries to further education, healthcare and community service locally and globally.
Acquire the knowledge and skills you need to break barriers in cancer and cell biology. Explore our research. Our Program We have incorporated the best elements of traditional graduate programs — academic rigor and stellar faculty — with flexibility that supports intensive academic training in small group formats while providing you the freedom and support necessary to design an individualized curriculum.
View curriculum. Where Will Your Ph. Take You? View alumni.Currently, we are not permitting visitors into our facilities, with very limited exceptions.
Read more. Our labs pursue research bridging basic and clinical cancer science with the goal of improving diagnosis, treatment, and prevention. Our multidisciplinary approach spans areas such as tumor progression and metastasis, tumor microenvironment, mechanisms of drug sensitivity and resistance, and epigenetic sources of tumorigenic traits.
Our close alliances with clinicians place us in a unique position, allowing the CBG Program to expedite translational research and make a significant impact on patient care. SKI offers a wide array of core facilities and other technologies, as well as significant opportunity for collaboration. Scientists in the CBG Program derive particular benefit from close ties to the following:. The deadline for the Fall Faculty Recruitment Search has now passed and applications are no longer being accepted.
Skip to main content. Our Faculty Scott W. Robert Benezra, PhD Cancer biologist Robert Benezra studies the molecular mechanisms of tumor growth and metastatic progression using mouse models. In addition, he studies the spindle assembly checkpoint which ensures proper chromosome segregation and is often deregulated in cancer. Luis F. Parada uses genetically engineered mouse models to study neurofibromatosis, brain tumors, cancer stem cells, and tumor progression. Craig B. Thompson, MD Memorial Sloan Kettering President Craig Thompson studies molecular signaling pathways that regulate nutrient uptake and the role these pathways play in the regulation of cell growth and survival.
The disease focus is on lymphocyte malignancies and the basic science arm of the lab explores fundamental mechanisms that control aberrant mRNA translation programs in cancer. Work in these two research areas frequently intersects in surprising ways. Richard White, MD, PhD Cancer biologist and oncologist Richard White uses the zebrafish to dissect interactions between tumor cells and the microenvironment that promote metastasis.
Kenneth Offit, MD Cancer geneticist Kenneth Offit focuses on gene characterization; genetic and epidemiologic studies of cancer-predisposing alleles; and the therapeutic, prognostic, and psychosocial translation of these findings.
Elli Papaemmanuil, PhD Molecular geneticist Elli Papaemmanuil performs systematic interrogations of well annotated clinical trial cohorts in leukemia and cancer to explore how the compound genetic and clonal architecture in patients leukemias and tumors dictate clinical phenotype, disease progression and clinical outcomes.
Viviane Tabar, MD Physician-scientist Viviane Tabar focuses on stem cells as tools for brain repair and for modeling brain cancer. Fall Faculty Recruitment Search. Latest News. How the Zebrafish Got Its Stripes.